Synthesis and evaluation of analgesic, antiinflammatory and antiplatelet properties of new 2-pyridylarylhydrazone derivatives

AR Todeschini, ALP de Miranda, KCM da Silva…

Index: Todeschini, Adriane R.; De Miranda, Ana Luisa P.; Da Silva, Kelly Christine M.; Parrini, Sergio C.; Barreiro, Eliezer J. European Journal of Medicinal Chemistry, 1998 , vol. 33, # 3 p. 189 - 199

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Citation Number: 184

Abstract

This work describes recent results from our research program aiming at the synthesis and pharmacological evaluation of new compounds acting as antiinflammatory, analgesic and platelet antiaggregatory. In this paper the synthesis and the pharmacological profile as analgesic, antiinflammatory and anti-platelet of new functionalized 2-pyridylarylhydrazone derivatives 5a–r are discussed. This class of N-heterocyclic derivatives represents a new ...