Abstract The first chemical synthesis of the 3-deazaspongosine nucleoside is described, starting from commercially available 4-amino-2, 6-dichloropyridine. The key step is the introduction of required functional groups at the 2 and 6 positions of the 4-amino-3- nitropyridine without any conflict in the synthesis of nucleobase. Regioselective nucleophilic substitution with allyl alkoxide at the 2 position of 4-amino-2, 6-dimethoxypyridine, ...
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![4,6-二氯-1H-咪唑[4,5-C]吡啶结构式](https://image.chemsrc.com/caspic/493/2589-12-0.png)
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