Synthesis of aldehydes from dihydro-1, 3-oxazines

AI Meyers, A Nabeya, HW Adickes…

文献索引：Meyers,A.I. et al. Journal of Organic Chemistry, 1973 , vol. 38, p. 36 - 56

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被引用次数: 110

摘要

1 desirable to describe in detail the studies which led to the successful implementation of this process. The anticipated approach required that (a) a readily available dihydro-1, 3- oxazine be utilized as starting material,(b) a stable carbanion be generated by the use of some suitablc base,(c) reaction of the carbanion with carbon electrophiles lead only to C- alkylation, since IS-alkylation would result in an undesirable side product,(d) a mild and ...