Synthesis and pharmacological activity of alkylphosphonic and oxy derivatives

…, AK Brel', GV Strel'tsova, NN Skladonovskaya…

文献索引：Tyurenkov, I. N.; Brel', A. K.; Strel'tsova, G. V.; Skladonovskaya, N. N.; Nazarenko, V. N. Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 2 p. 120 - 123 Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 2 p. 170 - 174

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摘要

There has recently been greater renewed interest in the search for physiologically active substances among phosphorus-containing compounds. In a further elaboration of that interest we tested the vascular and neurotropic activity of newly synthesized oxy derivatives of alkylphosphonic acids. The l-oxyphonates are among the most thoroughly studied phos" phorylated alkanes. The biological activity of the 2 (3)-oxydialkylphosphonates has not ...