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Cyclization of N-β-Cyanoethylanilines

WS Johnson, W DeAcetis

文献索引:Johnson; DeAcetis Journal of the American Chemical Society, 1953 , vol. 75, p. 2766

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被引用次数: 4

摘要

produced in 47% yield; therefore it seems likely that some intermediate temperature will give improved yields of IV (R= Cl). Preliminary attempts to eliminate the cyanoethyl group from IV (R= H) with base were not successful. Treatment with a mixture of concentrated hydrochloric acid and excess acetic anhydride however, yielded I11 (R= H), isolated as the N-acetyl derivative.