Abstract The stability of chlorambucil and its degradation product 4-[p-(2-chloroethyl-2- hydroxyethylamino) phenyl] butyric acid (I) was studied using reversed-phase high-pressure liquid chromatography. The degradation rate of chlorambucil was unaffected by pH between pH 5 and 10 but decreased at lower pH. The degradation rates of chlorambucil and I differed only slightly (pH> 6). The proteolytic properties of the compounds were studied using ...
![Benzenebutanoic acid,4-[(2-chloroethyl)(2-hydroxyethyl)amino]-结构式](https://image.chemsrc.com/caspic/246/27171-89-7.png)