Biological and Pharmaceutical Bulletin

Synthesis and pharmacological activities of hydrazones, Schiff and Mannich bases of isatin derivatives.

SK Sridhar, A Ramesh

文献索引：Sridhar, Seshaiah Krishnan; Ramesh, Atmakuru Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 10 p. 1149 - 1152

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被引用次数: 123

摘要

Schiff bases and phenyl hydrazone of isatins were prepared by reacting isatin and the appropriate aromatic primary amine/hydrazines. A new series of the corresponding N- mannich bases were synthesized by reacting them with formaldehyde and diphenylamine. The chemical structures were confirmed by means of their 1 H-NMR, IR spectral data and elemental analysis. The compounds were screened for analgesic, antiinflammatory and ...