Tetrahedron Letters

Total synthesis of carbomycin B and josamycin (leucomycin A 3)

K Tatsuta, Y Amemiya, S Maniwa, M Kinoshita

文献索引：Tatsuta, Kuniaki; Amemiya, Yoshiya; Maniwa, Shunji; Kinoshita, Mitsuhiro Tetrahedron Letters, 1980 , vol. 21, p. 2837 - 2840

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被引用次数: 46

摘要

Abstract The stereospecific total synthesis of macrolide antibiotics, carbomycin B and josamycin (leucomycin A 3), is described. The key aglycone has been synthesized by coupling two segments of C1–C10 and C11–C16 portions, which are stereospecifically derived from glucose.