The Reaction of Epichlorohydrin with the Grignard Reagent

JK Magrane Jr, DL Cottle

文献索引：Magrane; Cottle Journal of the American Chemical Society, 1942 , vol. 64, p. 486

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被引用次数: 20

摘要

The reaction of epichlorohydrin with Grignard reagents has been reported by many workers. Some1 obtained only 1, 3-dihalo-2-propanols while others? obtained the same substance as the major product and l-chloro-3-alkyl (or aryl)-2-propanols. It has long been known that, when a Grignard reagent is treated with ethylene oxide at room temperature or belowI3 the main product is an ethylene halohydrin and that the condensation product can be ...