The Journal of Organic Chemistry

Cobalt carbonyl-mediated Michael addition: direct synthesis of esters containing other functional groups from activated olefins

A Sisak, F Ungvary, L Marko

文献索引：Sisak, Attila; Ungvary, Ferenc; Marko, Laszlo Journal of Organic Chemistry, 1990 , vol. 55, # 8 p. 2508 - 2513

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被引用次数: 16

摘要

Hydrocarbalkoxylation of acrylonitrile with stoichiometric amounts of alcohols in the presence of catalytic amounts of CO&CO)~ and pyridine bases leads to 2, 4-dicyano-2- methylbutanoic acid esters. The yield of these Michael adducts shows a maximum as a function of the pyridine/cobalt ratio. Analogous reactions using equimolar amounts of alcohol, acrylonitrile, and an other activated olefin result in products with at least three ...