Non-peptide glycoprotein IIb/IIIa inhibitors. 17. Design and synthesis of orally active, long-acting non-peptide fibrinogen receptor antagonists

BC Askew, RA Bednar, B Bednar…

文献索引：Journal of Medicinal Chemistry, , vol. 40, # 12 p. 1779 - 1788

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被引用次数: 54

摘要

... Journal of Medicinal Chemistry. ... Chemistry. The pyrazolopiperazinone analog 1 was prepared as illustrated in Schemes 1 and 2. The N-terminal piperidine moiety utilized in all of the analogs was derived from commercially ...