Non-peptide glycoprotein IIb/IIIa inhibitors. 17. Design and synthesis of orally active, long-acting non-peptide fibrinogen receptor antagonists

BC Askew, RA Bednar, B Bednar…

Index: Journal of Medicinal Chemistry, , vol. 40, # 12 p. 1779 - 1788

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Citation Number: 54

Abstract

... Journal of Medicinal Chemistry. ... Chemistry. The pyrazolopiperazinone analog 1 was prepared as illustrated in Schemes 1 and 2. The N-terminal piperidine moiety utilized in all of the analogs was derived from commercially ...

Non-peptide glycoprotein IIb/IIIa inhibitors. 17. Design and...

[Askew, Benny C.; Bednar, Rodney A.; Bednar, Bohumil; Claremon, David A.; Cook, Jacquelynn J.; McIntyre, Charles J.; Hunt, Cecila A.; Gould, Robert J.; Lynch, Robert J.; Lynch Jr., Joseph J.; Gaul, Stanley L.; Stranieri, Maria T.; Sitko, Gary R.; Holahan, Marie A.; Glass, Joan D.; Hamill, Terrence; Gorham, Lynn M.; Prueksaritanont, Thomayant; Baldwin, John J.; Hartman, George D. Journal of Medicinal Chemistry, 1997 , vol. 40, # 12 p. 1779 - 1788]

Muscarinic M 3 receptor antagonists with (2R)-2-[(1R)-3, 3-D...

[Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 13 p. 2167 - 2172]