The Journal of organic chemistry

N, N-(Dimethylamino)-2-pyrrolidinones from the rearrangement of N-allyl-N', N'-dimethyl-2, 2-dichlorohydr-azides promoted by CuCl-N, N, N', N'- …

F Ghelfi, AF Parsons

文献索引：Ghelfi, Franco; Parsons, Andrew F. Journal of Organic Chemistry, 2000 , vol. 65, # 19 p. 6249 - 6253

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被引用次数: 46

摘要

Owing to their important biological properties, 2-pyrrolidinones have received considerable attention by researchers and the interest continues to bloom. 1 The γ-lactam ring is frequently found in important drugs used in medicine. 2 Moreover, other bioactive molecules can be easily obtained by reduction of the 2-pyrrolidinone nucleus to give pyrrolidines, 3 or by cleavage of the amide bond. 4 The search for new procedures for the synthesis of 2- ...