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d??Glucose as a Regioselectively Addressable Scaffold for Combinatorial Chemistry on Solid Phase

…, F Nicotra, CP Leslie, F Micheli, P Seneci…

文献索引:Peri, Francesco; Nicotra, Francesco; Leslie, Colin P.; Micheli, Fabrizio; Seneci, Pierfausto; Marchioro, Carla Journal of Carbohydrate Chemistry, 2003 , vol. 22, # 1 p. 57 - 71

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被引用次数: 14

摘要

d??Glucose derivatives bearing an anomeric thiophenyl group and orthogonally protections on secondary hydroxyl groups were linked to solid supports (PS/DV polymer, tentagel resin) through an ester bond on C??6. It was investigated the possibility to remove orthogonally protecting groups and functionalize selectively the free hydroxyls groups and the anomeric carbon of sugars in solid phase.