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Efficient Synthesis of 3??Pyrrolylquinolines via an 1, 3??Dipolar Cycloaddition/Oxidation Sequence

H Menasra, A Kedjadja, A Debache, S Rhouati…

文献索引:Menasra; Kedjadja; Debache; Rhouati; Belfaitah; Carboni, Bertrand Synthetic Communications, 2005 , vol. 35, # 21 p. 2779 - 2788

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被引用次数: 25

摘要

Abstract The synthesis of some new functionalized quinolyl derivatives relies on the 1, 3?? dipolar cycloaddition of an azomethine ylide, generated from sarcosine and paraformaldehyde, to quinolyl α, β??unsaturated esters, followed by oxidation of the pyrrolidinyl moiety to pyrrole with activated MnO2.