A total synthesis of horsfiline via aryl radical cyclisation

K Jones, J Wilkinson

文献索引：Jones, Keith; Wilkinson, James Journal of the Chemical Society, Chemical Communications, 1992 , # 24 p. 1767 - 1769

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被引用次数: 22

摘要

A Total Synthesis of Horsfiline via Aryl Radical Cyclisation ... Keith Jones* and James Wilkinson Department of Chemistry, King's College London, Strand, London WC2R 2LSf UK ... Cyclisation of 15 viathe derived aryl radical leads to spiropyrrolidinyl-oxindole 16, which is converted in three steps into the oxindole alkaloid horsfiline 3. ... As part of an approach to indole alkaloids of the aspidosperma and strychnos type, we have been interested in using aryl radical ...