Design, synthesis and molecular modeling study of iminodiacetyl monohydroxamic acid derivatives as MMP inhibitors

MA Santos, SM Marques, T Tuccinardi, P Carelli…

文献索引：Bioorganic and Medicinal Chemistry, , vol. 14, # 22 p. 7539 - 7550

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被引用次数: 35

摘要

... Bioorganic & Medicinal Chemistry. ... with the inhibition of these enzymes, MMPs have been a major target of drug-based medicinal chemistry research. ... selective inhibitory activity on MMPs, are in great demand and many research groups and pharmaceutical companies are ...