Tetrahedron

One-pot synthesis of monosubstituted aryl (hetaryl) acetylenes by direct introduction of the C CH residue into arenes and hetarenes

SF Vasilevsky, SV Klyatskaya, J Elguero

文献索引：Vasilevsky, Sergei F.; Klyatskaya, Svetlana V.; Elguero, Jose Tetrahedron, 2004 , vol. 60, # 31 p. 6685 - 6688

全文：HTML全文

被引用次数: 21

摘要

The diverse and high reactivity of the CC bond and the unusually high CH-acidity of monosubstituted acetylenes has determined an unabated interest on 1-alkynes for many years. 1., 2., 3. and 4. The CCH moiety is susceptible of nucleophilic, electrophilic, radical and cycloaddition reactions, and can be used both for functionalizing and building up C–C bonds. In fact, terminal acetylenes are very important key-compounds in the widely applied Mannich, 5 Hay, 6 ...