4-Arylazo-3, 5-diamino-1 H-pyrazole CDK inhibitors: SAR study, crystal structure in complex with CDK2, selectivity, and cellular effects

V Kryštof, P Cankar, I Fryšová, J Slouka…

文献索引：Journal of Medicinal Chemistry, , vol. 49, # 22 p. 6500 - 6509

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被引用次数: 106

摘要

... Journal of Medicinal ... DD1 5JJ, Scotland, United Kingdom, Laboratory of Experimental Medicine, Department of Pediatrics, Faculty of Medicine, Palacký University ... at the level of RNA polymerase II (RNAP-II) have recently attracted interest among medicinal chemists because of ...