On the Chemistry of Cinnoline V [1]. Reactions of 4-Aminocinnolines with Amines

AM Amer, MM El-Mobayed, S Asker

文献索引：Amer, Atef M.; El-Mobayed, Mathat M.; Asker, Sherif Monatshefte fur Chemie, 2004 , vol. 135, # 5 p. 595 - 604

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被引用次数: 7

摘要

Summary. We describe the effect of the solvent during the intra-cyclization of the arylhydrazonomalononitrile to obtain new and useful substituted cinnolines, namely 4-amino- 3-cyanocinnolines and (4-amino-cinnolin-3-yl) arylmethanones. 4-Amino-3-cyano-5, 7- dimethyl-cinnoline was treated with n-hexylamine, cyclohexylamine, and isopropylamine to yield the corresponding cinnoline-3-carboxamidine derivatives. Furthermore, 4-amino-3- ...