Pseudobase formation in 2-methylpapaverinium cations and their biotransformation by enzymes of rat liver homogenates in vitro

D Walterová, V Preininger, L Dolejš…

文献索引：Walterova; Preininger; Dolejs; et al. Collection of Czechoslovak Chemical Communications, 1980 , vol. 45, # 3 p. 956 - 965

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被引用次数: 4

摘要

Abstract 2-Methylpapaverinium iodide (I), 2'-hydroxymethyl-2-methylpapaverinium iodide (IX), and 2-methyl-3, 4-dihydropapaverinium iodide (X. CH 3 I) form pseudobase by addition of hydroxide ions to the C (1)= N (+) bond. 2'-Hydroxymethyl-2-methyl-3, 4- dihydropapaverinium iodide (XV) and 2'-hydroxymethyl-2-methyl-9-oxo-3, 4- dihydropapaverinium iodide (XVI) react with hydroxide ions in aqueous medium under ...