Palladium/Copper??Catalyzed Di?螃窿?arylation of Acetic Acid Esters

B Song, T Himmler, LJ Goossen

文献索引：Song, Bingrui; Himmler, Thomas; Goossen, Lukas J. Advanced Synthesis and Catalysis, 2011 , vol. 353, # 10 p. 1688 - 1694

全文：HTML全文

被引用次数: 9

摘要

Abstract A bimetallic palladium/copper catalyst system was found to effectively promote the diarylation of alkyl acetates with aryl halides under unprecedentedly mild conditions. The phenanthroline-copper-phosphine catalyst stabilizes the enolate intermediate to the extent that the deprotonation of esters can be achieved even with the mild base potassium phosphate. The palladium tri-tert-butylphosphine co-catalyst mediates the coupling of the ...