Stereoselective synthesis of hexahydro-3-methyl-1-arylchromeno [3, 4-b] pyrrole and its annulated heterocycles as potent antimicrobial agents for human pathogens
Synthesis of a series of novel hexahydrochromenopyrrole analogues has been accomplished through an intramolecular 1, 3-dipolar cycloaddition (1, 3-DC reaction) of azomethine ylides, generated by the aldehyde induced decarboxylation of secondary ...