Design, synthesis, and biological evaluation of novel trifluoromethyl indoles as potent HIV-1 NNRTIs with an improved drug resistance profile

HX Jiang, DM Zhuang, Y Huang, XX Cao…

文献索引：Organic and Biomolecular Chemistry, , vol. 12, # 21 p. 3446 - 3458

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被引用次数: 7

摘要

... Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy ... NNRTIs was based on the Merck derivative L-737, 126 (1) 12 as a ... The carcinogenicity (predicted by CISOC-PSCT) 21 of compounds 10e, 10l, 10i, 10k, 10j ...