Hydroxamic acids as a novel family of serine racemase inhibitors: mechanistic analysis reveals different modes of interaction with the pyridoxal-5′-phosphate …
HE Hoffman, J Jirásková, P Cígler…
文献索引：Journal of Medicinal Chemistry, , vol. 52, # 19 p. 6032 - 6041
... Journal of Medicinal Chemistry. ... a common transition state, the external aldimine, identification of active-site directed inhibitors with high specificity is a particular challenge.(6) Nevertheless, several PLP-dependent enzymes have been recognized as pharmaceutical targets, as ...
