Biocatalytic Racemization of (Hetero) Aryl??aliphatic α??Hydroxycarboxylic Acids by Lactobacillus spp. Proceeds via an Oxidation–Reduction Sequence

…, M Hall, W Kroutil, R Stuermer, B Hauer…

文献索引：Nestl, Bettina M.; Glueck, Silvia M.; Hall, Melanie; Kroutil, Wolfgang; Stuermer, Rainer; Hauer, Bernhard; Faber, Kurt European Journal of Organic Chemistry, 2006 , # 20 p. 4573 - 4577

全文：HTML全文

被引用次数: 18

摘要

Abstract The biocatalytic racemization of a range of (hetero) aryl-and (di) aryl-aliphatic α- hydroxycarboxylic acids has been achieved by using whole resting cells of Lactobacillus spp. The essentially mild (physiological) reaction conditions ensure the suppression of undesired side reactions, such as elimination, decomposition or condensation. Cofactor/inhibitor studies using a cell-free extract of Lactobacillus paracasei DSM 20207 ...