Zn (II) complex for selective and rapid scission of protein backbone

M Yashiro, Y Kawakami, J Taya, S Arai…

文献索引：Yashiro, Morio; Kawakami, Yukiko; Taya, Jun-Ichi; Arai, Suguru; Fujii, Yuki Chemical Communications, 2009 , # 12 p. 1544 - 1546

全文：HTML全文

被引用次数: 6

摘要

A ZnII complex with an aldehyde group hydrolyzed porcine pancreatic elastase under mild conditions, pH 8.0, 50° C, by the Schiff base formation between the ZnII complex and the NH2 group in the protein, suggesting that a ZnII compound can be active toward peptide hydrolysis when it strongly binds to the substrate.