Synthesis, radical scavenging activity and structure–activity relationship of uric acid analogs

D Yasuda, K Takahashi, T Kakinoki, Y Tanaka…

文献索引：MedChemComm, , vol. 4, # 3 p. 527 - 529

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被引用次数: 9

摘要

... 4 Cytotoxicity on the HL-60 cell line. Conclusions. ... As a result, the moiety required for the antioxidant activity of UA was 2-CO and 7-NH or 9-NH because 5 and 6 had greater antioxidant activity than UA. Introduction of 3-NH, 8-CO, and 9-NH moieties to 5 increased the activity. ...