Tetrahedron letters

Cu (I)-catalyzed three component coupling protocol for the synthesis of quinoline derivatives

HZS Huma, R Halder, SS Kalra, J Das, J Iqbal

文献索引：Syeda Huma; Halder, Rajkumar; Singh Kalra, Swinderjeet; Das, Jagattaran; Iqbal, Javed Tetrahedron Letters, 2002 , vol. 43, # 36 p. 6485 - 6488

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被引用次数: 158

摘要

Quinolines and their derivatives are very important in medicinal chemistry because of their wide occurrence in natural products 1., , and and drugs. 2., , and The classical method of quinoline synthesis is Skraup's procedure. 3., and Quinolines can be prepared from aminoarenes and olefins using transition metal complexes as catalysts. 4. and 5. Also, quinolines can be synthesized from aminoarenes and aliphatic aldehydes under non-acidic conditions. 6 Most of these ...