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Cloning and heterologous expression of two aryl-aldehyde dehydrogenases from the white-rot basidiomycete Phanerochaete chrysosporium

T Nakamura, H Ichinose, H Wariishi

文献索引:Nakamura, Tomofumi; Ichinose, Hirofumi; Wariishi, Hiroyuki Biochemical and Biophysical Research Communications, 2010 , vol. 394, # 3 p. 470 - 475

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被引用次数: 10

摘要

We identified two aryl-aldehyde dehydrogenase proteins (PcALDH1 and PcALDH2) from the white-rot basidiomycete Phanerochaete chrysosporium. Both PcALDHs were translationally up-regulated in response to exogenous addition of vanillin, one of the key aromatic compounds in the pathway of lignin degradation by basidiomycetes. To clarify the catalytic functions of PcALDHs, we isolated full-length cDNAs encoding these proteins and ...