A facile phase-transfer catalysed synthesis of some β-ketosulphones

…, J Ramanatham, JS Grossert, DL Hooper

文献索引：Ramaiah; Dubey; Ramanatham; Grossert; Hooper Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999 , vol. 38, # 3 p. 297 - 301

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被引用次数: 10

摘要

Abstract: Reaction of phenacyl chloride with sodium benzenesulphinate in refluxing alcohol for 10-12 hr results in the formation of phenylsulphonylacetophenone in about 50% yield. However, use of triethylbenzylammonium chloride as phase-transfer catalyst in acetonitrile medium at room temp. gives the product in over 90% yield in 30 min's, reaction time. Optimum conditions are described for the above reaction by changing the solvent, catalyst ...