Angewandte Chemie International Edition

Asymmetric Synthesis of Chiral 1, 3??Diaminopropanols: Bisoxazolidine??Catalyzed C C Bond Formation with α??Keto Amides

H Xu, C Wolf

文献索引：Xu, Hanhui; Wolf, Christian Angewandte Chemie - International Edition, 2011 , vol. 50, # 51 p. 12249 - 12252

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被引用次数: 18

摘要

The ever-increasing demand for enantiopure drugs and agrochemicals, and the use of chiral building blocks in polymers, liquid crystals, and other materials has generated a strong stimulus for the development of asymmetric methods that utilize previously unexplored starting materials to generate efficient access to new and emerging target compounds.[1] New drug candidates that bear a chiral 1, 3-diaminopropanol moiety or a corresponding ...