Rapid optimization of the hydrolysis of N'-trifluoroacetyl-S-tert-leucine-N-methylamide using high-throughput chemical development techniques

VW Rosso, JL Pazdan, JJ Venit

文献索引：Organic Process Research and Development, , vol. 5, # 3 p. 294 - 298

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被引用次数: 16

摘要

... as design of experiments 2 (DOE), and high-throughput synthetic techniques that allow process chemists to ... us to quickly develop the scientific understanding necessary for the implementation of processes at pilot ... organic, potassium tert butoxide, 48.6, 2.5, x, 4.9, 3.8, 3.1, 2.1, 10.8. ...