The Journal of organic chemistry

Synthesis of 3-substituted 4-aroylisoquinolines via Pd-catalyzed carbonylative cyclization of 2-(1-alkynyl) benzaldimines

G Dai, RC Larock

文献索引：Journal of Organic Chemistry, , vol. 67, # 20 p. 7042 - 7047

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被引用次数: 101

摘要

... The Journal of Organic ... Iowa 50011. J. Org. Chem. ... The optimal amount of the organic amine base has been studied. While 5 equiv of (n-Bu) 3 N was initially employed, mechanistically only 1 equiv of the base is required. We therefore examined the reaction using less base. ...