Molecules

Synthesis and in vitro protein tyrosine kinase inhibitory activity of furan-2-yl (phenyl) methanone derivatives

FL Zheng, SR Ban, XE Feng, CX Zhao, W Lin, QS Li

文献索引：Zheng, Fei Lang; Ban, Shu Rong; Feng, Xiu E; Zhao, Cheng Xiao; Lin, Wenhan; Li, Qing Shan Molecules, 2011 , vol. 16, # 6 p. 4897 - 4911

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被引用次数: 7

摘要

Abstract A series of novel furan-2-yl (phenyl) methanone derivatives were synthesized, and their structures were established on the basis of 1 H-NMR, 13 C-NMR and mass spectral data. All the prepared compounds were screened for their in vitro protein tyrosine kinase inhibitory activity and several new derivatives exhibited promising activity, which, in some cases, was identical to, or even better than that of genistein, a positive reference ...