Synthesis and biological activities of 4-phenyl-5-pyridyl-1, 3-thiazole derivatives as p38 MAP kinase inhibitors

S Miwatashi, Y Arikawa, K Naruo, K Igaki…

文献索引：Chemical and Pharmaceutical Bulletin, , vol. 53, # 4 p. 410 - 418

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被引用次数: 22

摘要

... Chemistry The general approach for the synthesis of 4,5-disubstituted 2-acetylamino-1,3-thiazoles 7 is outlined in Chart 1. The 1 ... Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd.; 2–17–85 Jusohonmachi, Yodogawa-ku, Osaka, 532–8686, Japan. ... Vol. ...