Synthetic communications

Mild and solvent??free alkynylation of ketones on the KF/alumina

A Sharifi, M Mirzaei, MR Naimi??Jamal

文献索引：Sharifi, Ali; Mirzaei, Mojtaba; Naimi-Jamal, M. Reza Synthetic Communications, 2005 , vol. 35, # 8 p. 1039 - 1044

全文：HTML全文

被引用次数: 12

摘要

View all references One significant example is alkynylation of carbonyl compounds for the preparation of propargylic alcohols. The traditional approach to these reactions involves the addition of alkynylide anions to carbonyl compounds. This process requires the conversion of alkynes to corresponding alkynylide anions using 1 equiv. of a strong air??sensitive base such as Grignard reagent,2 View all references alkyl lithium,3 View all references or sodium amide46. Saunders , JH 1955. ...