Tetrahedron Letters

Electrophilic carbon transfer in gold catalysis: synthesis of substituted chromones

J Renault, Z Qian, P Uriac, N Gouault

文献索引：Renault, Jacques; Qian, Zhao; Uriac, Philippe; Gouault, Nicolas Tetrahedron Letters, 2011 , vol. 52, # 19 p. 2476 - 2479

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被引用次数: 21

摘要

Abstract Using easily accessible aromatic alkoxy-arylalkynones, we have investigated the gold-catalyzed intramolecular addition of ethers to alkynes, to give easy access to various substituted chromones. This reaction involves the transfer of the ether substituent via a carbodemetallation process. We also noticed a competing isomerization of several starting materials for which we propose a second gold catalyzed mechanism.