Rhodium??Catalyzed Cycloisomerization Involving Cyclopropenes: Efficient Stereoselective Synthesis of Medium??Sized Heterocyclic Scaffolds

F Miege, C Meyer, J Cossy

文献索引：Miege, Frederic; Meyer, Christophe; Cossy, Janine Angewandte Chemie - International Edition, 2011 , vol. 50, # 26 p. 5932 - 5937

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被引用次数: 54

摘要

The intramolecular cyclopropanation of an olefin using a carbene that is generated by the decomposition of a diazo compound in the presence of a catalytic amount of a transition- metal complex, is a powerful strategy for the synthesis of [n. 1.0] bicyclic ring systems.[1] In recent years, the transition-metal-catalyzed cycloisomerization of enynes has emerged as a useful complementary alternative method that avoids the use of the potentially hazardous ...