A structurally simple self-immolative reagent that provides three distinct, simultaneous responses per detection event

SA Nuñez, K Yeung, NS Fox…

文献索引：Nunez, Sean A.; Yeung, Kimy; Fox, Nicole S.; Phillips, Scott T. Journal of Organic Chemistry, 2011 , vol. 76, # 24 p. 10099 - 10113

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被引用次数: 15

摘要

A general design is presented for a stimulus-responsive small molecule that is capable of responding to a specific applied chemical or physical signal by releasing two different types of pendant small molecules and a colorimetric indicator simultaneously. A key aspect of this design is the ease with which these reagents are prepared: typically, only four synthetic steps are required. Moreover, the modular construction strategy provides access to stimuli ...