Synthesis and antispasmodic activity of lidocaine derivatives endowed with reduced local anesthetic action

JCS Costa, JS Neves, MVN de Souza…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 3 p. 1162 - 1166

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被引用次数: 13

摘要

... Bioorganic & Medicinal Chemistry Letters. ... The present structure-activity relationship (SAR) study focused on chemical modifications of the structure of the local anesthetic lidocaine, and indicated analogues having reduced anesthetic potency, but with superior potency relative ...