Organometallics

Structure of bis (trifluoromethyl) cuprate and its role in trifluoromethylation reactions

GG Dubinina, J Ogikubo, DA Vicic

文献索引：Dubinina, Galyna G.; Furutachi, Hideki; Vicic, David A. Journal of the American Chemical Society, 2008 , vol. 130, # 27 p. 8600 - 8601

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被引用次数: 128

摘要

An equilibrium between [(SIMes) Cu-CF3](1) and the cuprate salt [(SIMes) 2Cu][(CF3) 2Cu](2) was observed. Synthetic methods to prepare and isolate 2 are reported. Trifluoromethylations using equilibrium mixtures of 1 and 2 occur readily for aryl iodides and even occur for aryl bromides at 90° C. Kinetic data suggest the cuprate form does not play a significant role in trifluoromethylations using N-heterocyclic carbene complexes of copper.