A selective fluorescent probe for the detection of mercury (II) in aqueous media and its applications in living cells

O García-Beltrán, N Mena, TA Berríos, EA Castro…

文献索引：Garcia-Beltran, Olimpo; Cassels, Bruce K.; Mena, Natalia; Nunez, Marco T.; Berrios, Tania A.; Castro, Enrique A.; Aliaga, Margarita E. Tetrahedron Letters, 2012 , vol. 53, # 48 p. 6598 - 6601,4

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被引用次数: 14

摘要

In this Letter we present a new probe, 2-amino-3-hydroxy-2-(hydroxymethyl) propyl 2-(7- hydroxy-2-oxo-2H-chromen-4-yl) acetate (PMR), which can reversibly detect mercuric ions (Hg2+) in HEPES buffer under physiological conditions. Possible interference with other analytes was examined. PMR displays a highly selective decrease of its fluorescence at 460nm when it reacts with Hg2+. Interestingly, the probe can also be used as a ...