Chemistry–A European Journal

Highly Chemo??and Stereoselective Intermolecular Coupling of Diazoacetates To Give cis??Olefins by Using Grubbs Second??Generation Catalyst

DM Hodgson, D Angrish

文献索引：Hodgson, David M.; Angrish, Deepshikha Chemistry - A European Journal, 2007 , vol. 13, # 12 p. 3470 - 3479

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被引用次数: 33

摘要

Abstract Highly stereoselective formation of cis-2-ene-1, 4-diesters by homo-and heterocoupling of α-diazoacetates in the presence of Grubbs second-generation catalyst is demonstrated. The dual reactivity of the catalyst in alkene metathesis and diazocoupling has been exploited in the synthesis of 12–26-membered macrocyclic dienyl dilactones by one- pot carbene dimerisation/ring-closing metathesis.