Synthesis and antiprotozoal activity of some 2-(trifluoromethyl)-1H-benzimidazole bioisosteres

G Navarrete-Vázquez…

文献索引：European Journal of Medicinal Chemistry, , vol. 41, # 1 p. 135 - 141

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被引用次数: 78

摘要

... European Journal of Medicinal Chemistry. ... Thus, bioisosterism represents one approach used by the medicinal chemist for the rationale modification of lead compounds into safer and ... shifts are given in ppm relative to tetramethylsilane (Me 4 Si, δ = 0) in CDCl 3 ; J values are ...