Synthesis and antiprotozoal activity of some 2-(trifluoromethyl)-1H-benzimidazole bioisosteres

G Navarrete-Vázquez…

Index: European Journal of Medicinal Chemistry, , vol. 41, # 1 p. 135 - 141

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Citation Number: 78

Abstract

... European Journal of Medicinal Chemistry. ... Thus, bioisosterism represents one approach used by the medicinal chemist for the rationale modification of lead compounds into safer and ... shifts are given in ppm relative to tetramethylsilane (Me 4 Si, δ = 0) in CDCl 3 ; J values are ...

Efficient solution phase synthesis of 2-(N-acyl)-aminobenzim...

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Synthesis and antiprotozoal activity of some 2-(trifluoromet...

[Navarrete-Vazquez, Gabriel; Rojano-Vilchis, Maria De Monserrat; Yepez-Mulia, Lilian; Melendez, Victor; Gerena, Lucia; Hernandez-Campos, Alicia; Castillo, Rafael; Hernandez-Luis, Francisco European Journal of Medicinal Chemistry, 2006 , vol. 41, # 1 p. 135 - 141]

Discovery of a 1, 5-dihydrobenzo [b][1, 4] diazepine-2, 4-di...

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Antihypertensive agents. I. Non-diuretic 2H-1, 2, 4-benzothi...

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