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General procedure for acylation of 3 alcohols: Scandium triflate/DMAP reagent

H Zhao, A Pendri, RB Greenwald

文献索引:Zhao, Hong; Pendri, Annapurna; Greenwald, Richard B. Journal of Organic Chemistry, 1998 , vol. 63, # 21 p. 7559 - 7562

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被引用次数: 81

摘要

Acylation of alcohols and the esterification of carboxylic acids are among the most frequently used processes in organic synthesis. This situation has led to the development of a host of methodologies with which to accomplish this conversion. By comparison with the ease of acylation of primary and secondary alcohols, tertiary alcohol acylation still remains a challenging problem. Typically, acylation of alcohols is performed with activated ...