General procedure for acylation of 3 alcohols: Scandium triflate/DMAP reagent

H Zhao, A Pendri, RB Greenwald

Index: Zhao, Hong; Pendri, Annapurna; Greenwald, Richard B. Journal of Organic Chemistry, 1998 , vol. 63, # 21 p. 7559 - 7562

Full Text: HTML

Citation Number: 81

Abstract

Acylation of alcohols and the esterification of carboxylic acids are among the most frequently used processes in organic synthesis. This situation has led to the development of a host of methodologies with which to accomplish this conversion. By comparison with the ease of acylation of primary and secondary alcohols, tertiary alcohol acylation still remains a challenging problem. Typically, acylation of alcohols is performed with activated ...