Regioselective carbonyl amination using diisobutylaluminum hydride

H Yamamoto, K Maruoka

文献索引：Yamamoto,H.; Maruoka,K. Journal of the American Chemical Society, 1981 , vol. 103, p. 4186

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被引用次数: 86

摘要

Abstract: A new, selective, and mild approach to N-alkylation of polyamines has been demonstrated, which involves the novel reductive cleavage of the CN bond in cyclic amidines by diisobutylaluminum hydride. This method provides a new entry to a wide variety of N-alkylated polyamines and many interesting macrocyclic polyamines hitherto accessible only by lengthy or complicated synthesis.