Journal of Fluorine Chemistry

Reactions of polyfluoropyridines with bidentate nucleophiles: attempts to prepare deazapurine analogues

PL Coe, AJ Rees, J Whittaker

文献索引：Coe, Paul L.; Rees, Anthony J.; Whittaker, Jane Journal of Fluorine Chemistry, 2001 , vol. 107, # 1 p. 13 - 22

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被引用次数: 10

摘要

Reactions of pentafluoropyridine with guanidine, thiourea and urea with the hope of preparing derivatives which may be cyclised to polyfluorodeazapurines are described The reactions with urea and thiourea produced, somewhat unexpectedly, bis-(2, 3, 5, 6- tetrafluoro-4-pyridyl) amine and bis-(2, 3, 5, 6-tetrafluoro-4-pyridyl) sulfide, respectively, the structure of the amine was confirmed by X-ray crystallography. The product from the ...